• Otolaryngologists frequently encounter patients with complaints of headaches. On occasion, normal physical examination findings may be accompanied by a roentgenographic enlargement of the sella turcica. In the process of evaluation for an intrasellar neoplasm, an "empty sella" is occasionally discovered. Patients with this condition commonly have headaches, although a cause-effect relationship is controversial. Endocrine and visual disturbances, although rare, necessitate periodic evaluation of these patients.
(Arch Otolaryngol Head Neck Surg 1986;112:883-885)
Browne JD, Kohut RI. Headache and the Primary Empty Sella Syndrome. Arch Otolaryngol Head Neck Surg. 1986;112(8):883–885. doi:10.1001/archotol.1986.03780080083019
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