• A retrospective study of 27 patients treated for stage I squamous cell carcinoma of the floor of the mouth was performed to assess the effectiveness of therapy. Of these patients, 23 (85%) underwent surgical therapy. Four patients (15%) were treated with radiation therapy alone, and three (11%) underwent combined surgery and radiation treatment. Initial treatment failed in seven patients (26%), and further therapy was curative in only four of seven. This small study suggests that stage I floor-of-the-mouth squamous cell carcinoma is not an easy lesion to cure. Other studies support these data. A three-dimensional monobloc resection with a 2-cm margin, including resection of the submandibular glands, is advocated. Toluidine blue 0 mucosal staining and Mohs' chemosurgery are helpful adjuncts in determining the tumor margins.
(Arch Otolaryngol Head Neck Surg 1986;112:1085-1089)
Stage I floor-of-the-mouth (FOM) squamous cell carcinoma (SCC) should be a controllable disease; the
Yco MS, Cruickshank JC. Treatment of Stage I Carcinoma of the Anterior Floor of the Mouth. Arch Otolaryngol Head Neck Surg. 1986;112(10):1085–1089. doi:10.1001/archotol.1986.03780100073011
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