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October 1986

Treatment of Stage I Carcinoma of the Anterior Floor of the Mouth

Author Affiliations

From the Department of Otolaryngology, Naval Hospital, San Diego. Dr Yco is now with the US Naval Hospital, Yokosuka, Japan.

Arch Otolaryngol Head Neck Surg. 1986;112(10):1085-1089. doi:10.1001/archotol.1986.03780100073011

• A retrospective study of 27 patients treated for stage I squamous cell carcinoma of the floor of the mouth was performed to assess the effectiveness of therapy. Of these patients, 23 (85%) underwent surgical therapy. Four patients (15%) were treated with radiation therapy alone, and three (11%) underwent combined surgery and radiation treatment. Initial treatment failed in seven patients (26%), and further therapy was curative in only four of seven. This small study suggests that stage I floor-of-the-mouth squamous cell carcinoma is not an easy lesion to cure. Other studies support these data. A three-dimensional monobloc resection with a 2-cm margin, including resection of the submandibular glands, is advocated. Toluidine blue 0 mucosal staining and Mohs' chemosurgery are helpful adjuncts in determining the tumor margins.

(Arch Otolaryngol Head Neck Surg 1986;112:1085-1089)

Stage I floor-of-the-mouth (FOM) squamous cell carcinoma (SCC) should be a controllable disease; the