• Candida vegetations found in silicone voice prostheses used in postlaryngectomy voice rehabilitation are associated with prothesis dysfunction. Selective oropharyngeal decontamination with amphotericin B lozenges resulted in sharp decrease of oropharyngeal Candida concentrations with a subsequent reduction of yeast colonization on voice protheses and in tracheoesophageal fistula in ten patients. A case report suggests that this selective oropharyngeal decontamination can prolong the device's lifetime.
(Arch Otolaryngol Head Neck Surg 1986;112:1090-1092)
Mahieu HF, van Saene JJM, den Besten J, van Saene HKF. Oropharynx Decontamination Preventing Candida Vegetation on Voice Prostheses. Arch Otolaryngol Head Neck Surg. 1986;112(10):1090–1092. doi:10.1001/archotol.1986.03780100078012
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