[Skip to Navigation]
[Skip to Navigation Landing]
October 1986

Oropharynx Decontamination Preventing Candida Vegetation on Voice Prostheses

Author Affiliations

From the Ear, Nose, and Throat Clinic, University Hospital (Drs Mahieu and den Besten), and the Faculty of Pharmacy, Division of Microbiology, State University (Drs J. van Saene and H. van Saene), Groningen, the Netherlands.

Arch Otolaryngol Head Neck Surg. 1986;112(10):1090-1092. doi:10.1001/archotol.1986.03780100078012

• Candida vegetations found in silicone voice prostheses used in postlaryngectomy voice rehabilitation are associated with prothesis dysfunction. Selective oropharyngeal decontamination with amphotericin B lozenges resulted in sharp decrease of oropharyngeal Candida concentrations with a subsequent reduction of yeast colonization on voice protheses and in tracheoesophageal fistula in ten patients. A case report suggests that this selective oropharyngeal decontamination can prolong the device's lifetime.

(Arch Otolaryngol Head Neck Surg 1986;112:1090-1092)