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December 1986

Lesion Thickness Forecasts Prognosis of Oral Cavity Tumors

Arch Otolaryngol Head Neck Surg. 1986;112(12):1246. doi:10.1001/archotol.1986.03780120010001

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At a meeting of the Society of Head and Neck Surgery (May 7-10, 1986, Colorado Springs, Colo), on May 8, Dr Ronald H. Spiro and colleagues presented a report entitled "The Predictive Value of Tumor Thickness in Patients With Squamous Cell Carcinoma Confined to the Tongue and the Floor of the Mouth." One hundred five consecutive patients treated surgically for localized squamous cell carcinoma of the oral cavity were reviewed retrospectively to assess the impact of tumor thickness on therapeutic outcome. For patients whose lesions were 2 mL or less in thickness, the two-year determinant no-evidence-of-disease survival was 98%. In contrast, patients with tumors 3 to 8 mL in thickness or greater than 9 mL in thickness had two-year no-evidence-of-disease survivals of 83% and 65%, respectively. Tumor thickness was judged more sensitive than "T" stage in predicting local recurrence and metastasis of the cervical lymph nodes.

In a subsequent report,

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