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December 1986

Liposarcoma of the Larynx: Case Report and Literature Review

Author Affiliations

From the Department of Pathology (Drs Meis and Mackay) and Head and Neck Surgery (Dr Goepfert), The University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston.

Arch Otolaryngol Head Neck Surg. 1986;112(12):1289-1292. doi:10.1001/archotol.1986.03780120053010

• Primary liposarcoma of the larynx is extremely rare. To our knowledge, only eight cases have been documented in the English literature. We report a ninth case in a 54-year-old man. The recurrent 2-cm tumor was well differentiated and was treated with a supraglottic laryngectomy with partial neck dissection followed by radiotherapy. There has not been a second recurrence in 16 months. The majority of liposarcomas arising in the larynx have been of a favorable histologic type (well differentiated or myxoid). The tumor tends to occur in a supraglottic location in men of 40 years or more, and multiple recurrences are typical. The primary mode of treatment is wide surgical excision, with or without postoperative radiation therapy.

(Arch Otolaryngol Head Neck Surg 1986;112:1289-1292)