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November 1987

Carcinoma of the Subglottis: Results of Initial Radical Radiation

Author Affiliations

the ENT Group, The Princess Margaret Hospital
From the Department of Radiation Oncology (Drs Warde and Keane) and the ENT Group, The Princess Margaret Hospital, Toronto, and the Romagosa Radiation Oncology Centre, Lafayette, La (Dr Harwood).

Arch Otolaryngol Head Neck Surg. 1987;113(11):1228-1229. doi:10.1001/archotol.1987.01860110094015

• During the 12-year period 1971 to 1982, 23 patients with primary squamous cell carcinoma of the subglottis were treated with initial radical radiation therapy. There were 19 men and four women, with a mean age of 64 years. Five patients had T1 tumors, four had T2, three had T3, and 11 had T4. The actuarial overall and cause-specific survival rates were 26% and 61%, respectively. Local control was achieved with initial radiation therapy in 16 patients (70%). Subsequent local control was achieved in one other patient following surgery for recurrence, giving an ultimate local control figure of 74% (17 of 23 patients). All patients with T1, T2, and T3 disease achieved local control with initial treatment; however, seven of the 11 patients with T4 disease either had residual disease following radiation therapy or developed local recurrence on follow-up.

(Arch Otolaryngol Head Neck Surg 1987;113:1228-1229)

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