Osseointegration is defined by Dr P. I. Branemark as "a direct structural and functional connection between ordered living bone in the surface of a load-carrying implant." Through the research efforts of Dr Branemark and his colleagues in Sweden,1−3 these principles of osseointegration have been applied to clinical settings and are now being utilized widely in the United States.
The primary utilization, at the present time, involves the permucosal implantation of titanium fixtures intraorally that will become osseointegrated with time, following which they are able to support the loads and stresses of fixed dentures. This application is aiding thousands of individuals with atrophic mandibles or after mandibular reconstruction who, in the past, were unable to be satisfactorily orally rehabilitated.
Over the past two years, investigative centers in San Antonio, Tex, San Francisco, Minneapolis, and New York have been utilizing Food and Drug Administration (FDA)-approved clinical trials to demonstrate the efficacy
HOLT GR. Status of Osseointegrated Implants. Arch Otolaryngol Head Neck Surg. 1988;114(7):726–727. doi:10.1001/archotol.1988.01860190030014
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