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July 1988

Postrhinoplasty Epistaxis: Role of Vitamin E?

Author Affiliations

From the Department of Otolaryngology–Head and Neck Surgery, Division of Facial Plastic and Reconstructive Surgery, University of Southern California School of Medicine, Los Angeles (Dr Churukian); Department of Surgery, Division of Head and Neck Surgery, UCLA School of Medicine, Los Angeles (Drs Cohen, Kamer, and Zemplenyi); and Department of Medicine, Division of Hematology, The Memorial Hospital, Pawtucket, RI (Dr Steiner).

Arch Otolaryngol Head Neck Surg. 1988;114(7):748-750. doi:10.1001/archotol.1988.01860190052021

• Postrhinoplasty epistaxis occurred in two patients, both of whom were found to be ingesting megadoses of vitamin E. The rate of vitamin E consumption in a population of 100 uncomplicated nasal operations during this same period was 16%. A review of the medical literature on vitamin E found recent evidence demonstrating a marked decrease in platelet adhesiveness with megadose ingestion of vitamin E. It is concluded that this should be avoided in the perioperative period.

(Arch Otolaryngol Head Neck Surg 1988;114:748-750)