• Postrhinoplasty epistaxis occurred in two patients, both of whom were found to be ingesting megadoses of vitamin E. The rate of vitamin E consumption in a population of 100 uncomplicated nasal operations during this same period was 16%. A review of the medical literature on vitamin E found recent evidence demonstrating a marked decrease in platelet adhesiveness with megadose ingestion of vitamin E. It is concluded that this should be avoided in the perioperative period.
(Arch Otolaryngol Head Neck Surg 1988;114:748-750)
Churukian MM, Zemplenyi J, Steiner M, Kamer FM, Cohen A. Postrhinoplasty Epistaxis: Role of Vitamin E? Arch Otolaryngol Head Neck Surg. 1988;114(7):748–750. doi:10.1001/archotol.1988.01860190052021
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