To the Editor.—I am writing concerning the article about toxic shock syndrome after nasal surgery that appeared in the March 1988 issue of the Archives.
Jacobson et al1 have made a significant contribution to the otolarynologic literature in their article entitled "Evaluation of Single-Dose Cefazolin Prophylaxis for Toxic Shock Syndrome." This article appears to be a follow-up study from a similar article concerning toxic shock after nasal surgery published in the March 1986 issue of the Archives by Jacobsen et al.2 There was a statement in the March 1986 article that indicated systemic antibiotics did not have a demonstrable protective effect against toxic shock syndrome. The March 1988 article concluded that a regimen of single-dose cefazolin prophylaxis was unlikely to have a major effect on the incidence of toxic shock syndrome following nasal surgery. I must object to these conclusions from both studies. It continues to be a
KENNEDY KS. Toxic Shock Syndrome. Arch Otolaryngol Head Neck Surg. 1988;114(12):1477–1478. doi:https://doi.org/10.1001/archotol.1988.01860240127039
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