• Twenty-four patients with advanced paranasal sinus tumors were treated with combined superselective intra-arterial and systemic chemotherapy, yielding an immediate satisfactory tumor response rate of 91%, significantly better than previously reported. Eight patients had craniofacial surgery circumvented because of complete or near complete response. Repetitive uncomplicated catheterization of the pterygoid segment of the internal maxillary artery using a coaxial system is the cornerstone of successful induction chemotherapy. Strenuous screening of medical status is mandatory for this aggressive introduction chemotherapy.
(Arch Otolaryngol Head Neck Surg 1989;115:503-511)
Lee Y, Dimery IW, Tassel PV, Pena CD, Blacklock JB, Goepfert H. Superselective Intra-arterial Chemotherapy of Advanced Paranasal Sinus Tumors. Arch Otolaryngol Head Neck Surg. 1989;115(4):503–511. doi:10.1001/archotol.1989.01860280101026
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: