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August 1989

Radiation-Induced Sarcoma of the Thyroid

Author Affiliations

From the Departments of Therapeutic Radiology (Dr Griem), Otolaryngology and Bronchoesophagology (Drs Robb and Caldarelli), and Pathology (Dr Templeton), Rush-Presbyterian–St Luke's Medical Center, Chicago, Ill.

Arch Otolaryngol Head Neck Surg. 1989;115(8):991-993. doi:10.1001/archotol.1989.01860320101028

• A 23-year-old white man presented with a thyroid mass 12 years after receiving high-dose radiotherapy for a T2 and N1 lymphoepithelioma of the nasopharynx. Following subtotal thyroidectomy, a histopathologic examination revealed liposarcoma of the thyroid gland. The relationship between sarcomas and irradiation is described and Cahan and colleagues' criteria for radiation-induced sarcomas are reviewed. To our knowledge, we are presenting the first such case of a radiation-induced sarcoma of the thyroid gland.

(Arch Otolaryngol Head Neck Surg. 1989;115:991-993)

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