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September 1989

Allergic Aspects of Inner Ear Disease

Arch Otolaryngol Head Neck Surg. 1989;115(9):1028. doi:10.1001/archotol.1989.01860330018009

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At the recent 1989 Spring Meeting of the American Academy of Otolaryngic Allergy in San Francisco, Calif, Dr Jennifer Derebery, House Otologic Group, Los Angeles, Calif, shared her experience with the management of a series of 49 patients with Meniere's disease. Sixty-six percent of these patients had improvement of symptoms by control of inhalent and food allergies. The only consistent finding for predicting which patients will respond to treatment was total IgE, averaging 203 U for those who failed therapy. In one case, vertiginous symptoms worsened on attempts at desensitization, requiring cessation of therapy, and eventual eighth-nerve section. This was thought to be secondary to the documented initial rise in IgE (722 to 903 U), thus increasing the end-organ sensitivity.—Robert E. Taylor, MD, Oakland, Calif

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