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At the 31st annual meeting of the American Society for Head and Neck Surgery, held in San Francisco, Calif, April 5 and 6, 1989, Drs Scott Stern and James Suen, Little Rock, Ark, reported a retrospective study of the use of adjuvant radiotherapy in 30 patients with mucosal and advanced or recurrent cutaneous head and neck melanoma. Of 7 patients with mucosal melanoma, all treated with surgery and conventional postoperative radiotherapy, all died of disease within 16 months. The local control rate was 71% (5/7). In the 23 patients with advanced or recurrent cutaneous melanoma, the local control rate was 53% (9/17) in the group receiving a high dose per fraction of hypofractionated adjuvant radiotherapy vs 100% (6/6) in the group receiving conventionally fractionated adjuvant radiotherapy. The investigators interpreted these data to show that conventionally fractionated adjuvant radiotherapy is probably effective in obtaining local control of advanced head and neck melanoma
WEISSLER MC. Adjuvant Radiotherapy for Melanoma. Arch Otolaryngol Head Neck Surg. 1989;115(10):1162. doi:10.1001/archotol.1989.01860340016008
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