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December 1989

Hyperbaric Oxygenation for Necrotizing (Malignant) Otitis Externa

Author Affiliations

From the Departments of Otolaryngology (Drs Shupak, Greenberg, and Meyer) and Nuclear Medicine (Dr Hardoff), Carmel Lady Davis Hospital, and the Israeli Naval Hyperbaric Institute (Drs Shupak, Gordon, and Melamed), Haifa, Israel.

Arch Otolaryngol Head Neck Surg. 1989;115(12):1470-1475. doi:10.1001/archotol.1989.01860360072021

• Two patients with extensive necrotizing otitis externa have been treated by hyperbaric oxygenation. One patient had facial nerve palsy and the other suffered from skull base involvement. Due to severe side effects, the preferred combined intravenous antibiotic therapy was changed to monotherapy in one case and completely withdrawn in the second. This was done before the commencement of hyperbaric oxygenation, while the necrotizing infection was still active. Hyperbaric oxygenation therapy was followed by complete resolution of the necrotizing otitis externa, which did not recur. The pathogenesis of the disease and mechanisms by which hyperbaric oxygenation might be of benefit are described. We conclude that hyperbaric oxygenation should be considered as adjuvant therapy for necrotizing otitis externa whenever a therapeutic pressure chamber is available.

(Arch Otolaryngol Head Neck Surg. 1989;115:1470-1475)

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