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June 1990

The Pathologic and Thermal Effects of Gold Vapor Laser Photodynamic Therapy on the Larynx: Experimental Study

Author Affiliations

From the Department of Otolaryngology and Communicative Disorders, Long Island Jewish Medical Center, New Hyde Park, NY.

Arch Otolaryngol Head Neck Surg. 1990;116(6):687-691. doi:10.1001/archotol.1990.01870060045007

• A gold vapor laser, which emits short pulses of light at a wavelength of 628 nm, was used to deliver varying amounts of energy (30 to 120 J cm2) to the presensitized (dihematoporphyrin ether) canine larynx. Between 30 and 60 J/cm2, the larynx appeared normal, and when 70 to 100 J/cm2 was applied, only mild edema and erythema were seen. Simultaneously, a thermocouple probe was used and a 0.4°C to 1.5°C temperature rise found. Thus, the gold vapor laser seems capable of achieving the therapeutic photosensitizing effect without causing significant laryngeal edema or thermal activity.

(Arch Otolaryngol Head Neck Surg. 1990;116:687-691)

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