[Skip to Navigation]
December 1990

The Efficacy of Oral Steroids in the Treatment of Persistent Otitis Media With Effusion

Author Affiliations

From the Department of Otolaryngology, Bnai Zion Medical Center (Drs Podoshin, Fradis, and Ben-David), the Department of Medicine, Technion-Israel Institute of Technology (Drs Podoshin, Fradis, and Ben-David), and the Department of Statistics, Haifa University (Dr Faraggi), Haifa, Israel.

Arch Otolaryngol Head Neck Surg. 1990;116(12):1404-1406. doi:10.1001/archotol.1990.01870120050007

• One hundred thirty-six children with otitis media with effusion of at least 2 months' duration were investigated in a strict, double-blind, randomized prospective study to evaluate the efficacy of oral steroids in the treatment of this disease. The results of our study showed a significant complete and partial recovery from otitis media with effusion in the group treated by a combination of antibiotics (amoxicillin) and oral steroids (prednisone), compared with an amoxicillin-treated group and a placebo-treated group. We believe that this treatment mostly benefits children aged 4 to 10 years without oversized adenoids. The findings of our study imply that a combined course of antibiotics and oral steroids deserves its place as a routine conservative trial before surgery.

(Arch Otolaryngol Head Neck Surg. 1990;116:1404-1406)

Add or change institution