• In a 1-year prospective study, 60 patients with chronic serous otitis media underwent bilateral tympanocentesis with tube insertion. The right ear was treated with dexapolyspectran (a solution consisting of polymyxin B sulfate, neomycin sulfate, sulfonamide, and hydrocortisone) intraoperatively and for 72 hours afterward, and the left ear served as the control. All patients were followed up at weekly intervals for the first month. Five (8.3%) out of 60 experimental ears had purulent otorrhea within the first 14 days after surgery, compared with eight (13.3%) out of 60 control ears. Statistical analysis showed no difference between the two groups.
(Arch Otolaryngol Head Neck Surg. 1991;117:537)
Ramadan HH, Tarazi T, Zaytoun GM. Use of Prophylactic Otic Drops After Tympanostomy Tube Insertion. Arch Otolaryngol Head Neck Surg. 1991;117(5):537. doi:10.1001/archotol.1991.01870170083018
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.