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November 1991

The Effect of Postoperative Radiation Therapy on Pharyngoesophageal Reconstruction With Free Jejunal Interposition

Author Affiliations

From the Departments of Otolaryngology (Drs Petruzzelli, Johnson, Myers, and deVries, and Ms Wagner), Radiation Oncology (Dr Cano), and Plastic and Reconstructive Surgery (Drs Shestak and Jones), University of Pittsburgh (Pa) School of Medicine. Dr deVries is now with the University of Florida, Gainesville.

Arch Otolaryngol Head Neck Surg. 1991;117(11):1265-1268. doi:10.1001/archotol.1991.01870230081012

• Free tissue transfer of a jejunal segment was undertaken for laryngopharyngoesophageal reconstruction in 20 patients who received postoperative irradiation therapy. Treatment consisted of 1.8- to 2-Gyfractions, the average total dose was 55.57 Gy (range,40 to 66 Gy). Anastomotic strictures (six) were encountered early in the series and associated with stapled anastomoses. Hand-sewing the jejunoesophagostomy eliminated the problem. Enteric cutaneous fistula, bowel necrosis, and hemorrhagic enteritis were not observed. We conclude that the application of postoperative irradiation therapy to patients requiring jejunal interposition grafts is feasible.

(Arch Otolaryngol Head Neck Surg. 1991;117:1265-1268)

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