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September 1992

The First Branchial Cleft Carcinoma

Arch Otolaryngol Head Neck Surg. 1992;118(9):969-971. doi:10.1001/archotol.1992.01880090085022

• Primary branchiogenic carcinoma was previously a debated entity. Initially it was a popular diagnosis for many cystic carcinomas of the neck. Then, in 1950, stringent criteria were defined for establishing the diagnosis of primary branchiogenic carcinoma. Only a limited number of cases have successfully fulfilled these criteria. We describe a patient who meets the criteria and who we believe represents the first reported case of a carcinoma arising from the vestigium of the first branchial cleft. We also review the literature on branchial cleft carcinomas and discuss the diagnosis, histopathologic features, and therapeutic options.

(Arch Otolaryngol Head Neck Surg. 1992;118:969-971)