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October 1992

A Histologic Study of Nonmorphogenetic Forms of Hereditary Hearing Impairment

Author Affiliations

From the Department of Otolaryngology—Head and Neck Surgery, The University of Iowa, Iowa City (Dr Smith); Medical Research Council Institute of Hearing Research, University of Nottingham (England) (Dr Steel and Mr Barkway); and Otolaryngology/Audiology Department, St Mary's Hospital (Dr Soucek), and Department of Histopathology, University College and Middlesex School of Medicine (Dr Michaels), London, England.

Arch Otolaryngol Head Neck Surg. 1992;118(10):1085-1094. doi:10.1001/archotol.1992.01880100077016

• It appears that many forms of syndromic and nonsyndromic hereditary hearing impairment are secondary to either neuroepithelial or cochleosaccular dysfunction. Making this distinction can be difficult in human temporal bone specimens; however, this added knowledge may ultimately provide prognostic and therapeutic information in hearing habilitation. Fundamental studies using animal models of different types of hereditary deafness may also prove useful in this respect.

(Arch Otolaryngol Head Neck Surg. 1992;118:1085-1094)

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