To the Editor.—Nasal polyps have been recognized from 1000 bc1 and are said to be a disease of the ethmoid sinuses. Mucosal reactions at the cellular level, the relatively poorly developed blood supply of the ethmoid sinus, and the complex anatomy of the ethmoid labyrinth are factors implicated in the pathogenesis of polyps.2 With regard to the cause, Bernouilli phenomenon, polysaccharide changes, vasomotor imbalance, infection, and allergy are contributory factors.2 It is also known that if they are unilateral, transitional cell papilloma or malignancy have to be ruled out.2
We have seen patients with angiofibromas, fungal infections like aspergillosis, mucormycosis, and longstanding foreign bodies on the nose, who have presented to us as having unilateral nasal polyps, and rarely bilateral, particularly in fungal infections affecting the sphenoid sinus spreading intracranially. These polyps resemble nasal polyps on macroscopic as well as microscopic examination. Histologically only eosinophilia
RAMAN R. Nasal Polyps: A Sign of Disease. Arch Otolaryngol Head Neck Surg. 1992;118(10):1133. doi:10.1001/archotol.1992.01880100125026
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