—To see whether a cholinomimetic medication would help resolve the parotid gland enlargement associated with self-induced vomiting in bulimic patients.
—The medication was administered on an inpatient eating disorder unit to bulimic patients with refractory sialadenosis.
—Pilocarpine hydrochloride drops were administered orally at a dosage of 1.25 to 5.0 mg/d until the parotid gland enlargement was significantly reduced.
—There was a marked diminution in the size of the parotid gland enlargement.
—Pilocarpine has proved to be beneficial in the treatment of sialadenosis in bulimic patients.(Arch Otolaryngol Head Neck Surg. 1993;119:787-788)
Mehler PS, Wallace JA. Sialadenosis in Bulimia: A New Treatment. Arch Otolaryngol Head Neck Surg. 1993;119(7):787–788. doi:10.1001/archotol.1993.01880190083017
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