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We regret having missed the case report on liposarcoma of the larynx, published by Gertner et al in 1988. The article reviews the case of liposarcoma of the posterior left arytenoid in a 37-year-old man. The tumor pathology is well described and depicted in the original article.
The pathologic subclassification of this lesion is somewhat difficult. Overall, it appears to be a well-differentiated lesion; however, the noted presence of pathologic mitoses identified at a "not infrequent basis" would tend to push this lesion toward the pleomorphic subcategory or perhaps a well-differentiated lesion showing dedifferentiation. With this histologic finding, the patient received an appropriately aggressive approach. The patient apparently died in his fifth year of follow-up of both lung and bony metastases. This certainly would be consistent with the clinical course expected of a pleomorphic liposarcoma.
Since our article was published, I have also treated an additional case of
McCulloch TM, Makielski KH, McNutt MA. Laryngeal Liposarcoma-Reply. Arch Otolaryngol Head Neck Surg. 1993;119(12):1384. doi:10.1001/archotol.1993.01880240123021
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