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At the fall meeting of the American Academy of Facial Plastic and Reconstructive Surgery, David A. F. Ellis, MD, and his coauthors, Toronto, Ontario, presented a study outlining their search for a substance that could be used for subcutaneous soft-tissue facial augmentation that overcomes problems related to the materials currently available. Dr Trimas noted that collagen injection for facial augmentation has complications such as resorption, clumping, and the requirement of a large-bore needle for harvesting and injection as well as secondary donorsite complications. Dr Trimas noted that while silicone has been used for many years, it, too, has high complication rates such as migration, granuloma formation, and induction of autoimmune disease. Therefore, silicone is no longer available on the commercial market for human use. In an effort to overcome the problems inherent within the use of these facial soft-tissue augmentation materials, the authors undertook the study to evaluate the effectiveness
RICE DH, Alford EL. Subcutaneous Implantation of Microparticulate PTFE (Gore-Tex). Arch Otolaryngol Head Neck Surg. 1994;120(3):369. doi:10.1001/archotol.1994.01880270093017
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