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Tutkun is right in observing a very significant difference in the dosage reported in our two studies. The exact concentration of ciprofloxacin that we used in both studies was 250 μg/mL, which we obtained dissolving the pure powder of ciprofloxacin in saline solution. The only difference concerning the dosage was in the quantity of drops used: the first study mentioned three drops and the second study mentioned four drops according to the further suggestions of ear, nose, and throat specialists who were participating in the study.
I am sorry for the misunderstanding. It was my fault as in the original manuscript that I sent to the Archives it was a typographic mistake (both in the "Materials and Methods" and in the "Comment" sections) where 250 mg/mL instead of 250 μg/mL was mentioned. I did not notice this error even when I verified the page proofs of the article.
Esposito S. Ciprofloxacin-Reply. Arch Otolaryngol Head Neck Surg. 1994;120(8):886. doi:10.1001/archotol.1994.01880320086020
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