[Skip to Navigation]
September 1994

Terminal Duct Carcinoma: Recognition of a Low-Grade Salivary Adenocarcinoma

Author Affiliations

From the Division of Otolaryngology (Dr Lucarini) and the Department of Pathology (Drs Khettry and Nasser), New England Deaconess Hospital, Boston, Mass, and the Departments of Dental Medicine and Pathology, Long Island Jewish Medical Center, New Hyde Park, NY (Dr Sciubba). Dr Lucarini is now with the Department of Surgery, Division of Otolaryngology, Newton-Wellesley Hospital, Newton, Mass.

Arch Otolaryngol Head Neck Surg. 1994;120(9):1010-1015. doi:10.1001/archotol.1994.01880330088016

We describe six cases of terminal duct carcinoma of the minor salivary glands. All were localized to the oral cavity, without regional nodal or distant metastases. Histologically, five were originally mistaken for adenoid cystic carcinoma; one was interpreted as monomorphic adenoma with areas of adenoid cystic carcinoma. Treatment consisted of wide resection with or without radiation therapy, with no incidence of recurrence or metastasis. The characteristics of this recently described pathologic entity are reviewed. The less aggressive behavior of this tumor compared with adenoid cystic carcinoma should call for less radical therapy, with a favorable prognosis in most cases. Recognition of this tumor as a distinct clinical and pathologic entity is therefore important.

(Arch Otolaryngol Head Neck Surg. 1994;120:1010-1015)

Add or change institution