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June 1995

The Effect of Intradermal Corticosteroids on Skin Flap Edema

Author Affiliations

From the Section of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology and Communicative Sciences, Medical University of South Carolina, Charleston.

Arch Otolaryngol Head Neck Surg. 1995;121(6):654-657. doi:10.1001/archotol.1995.01890060052010

Objective:  To validate a model for skin flap edema in the piglet and determine whether intraoperative and postoperative intradermal corticosteroids reduce the edema created.

Design:  Prospective, randomized, matched-control animal model.

Setting:  Animal laboratory.

Participants:  Twenty-five weight-matched purebred Yorkshire piglets.

Intervention:  Intraoperative and postoperative injections of intradermal triamcinolone.

Main Outcomes Measured:  Flap edema.

Results:  A reproducible skin flap edema model was validated in the piglet. Intraoperative intradermal corticosteroids decreased flap edema but postoperative corticosteroids did not.

Conclusion:  Clinical improvement in skin flap and supratip fullness may result from mechanisms other than edema.(Arch Otolaryngol Head Neck Surg. 1995;121:654-657)