To characterize the otolaryngologic manifestations of amyloidosis; classify patients with amyloidosis by specific location and type of underlying disease; and compare disease presentation and long-term outcome in these patients.
Retrospective review of biopsy specimens recorded as amyloidosis.
Tertiary care referral center serving a diverse patient base.
Of 141 patients with biopsy-verified amyloidosis who met the inclusion criterion for the study, 27 (19%) had head and neck manifestations.
Good functional outcome and survival of patients with amyloidosis.
The tongue was the most commonly affected site of the head and neck. Distinct differences exist in functional outcome and long-term survival in patients with the localized form of amyloidosis when compared with patients with systemic amyloidosis.
Because amyloidosis often affects the head and neck, otolaryngologists need to be familiar with this disease.(Arch Otolaryngol Head Neck Surg. 1995;121:778-782)
Kerner MM, Wang MB, Angier G, Calcaterra TC, Ward PH. Amyloidosis of the Head and Neck: A Clinicopathologic Study of the UCLA Experience, 1955-1991. Arch Otolaryngol Head Neck Surg. 1995;121(7):778–782. doi:10.1001/archotol.1995.01890070064014
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