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September 1995

Metastatic Melanoma to the Cerebellopontine Angle: Clinical and Imaging Characteristics

Author Affiliations

From the Department of Otolaryngology, Wilford Hall Air Force Medical Center, Lackland Air Force Base, Tex (Dr Arriaga); the Department of Radiology, St Vincent Medical Center, Los Angeles, Calif (Dr Lo); and the House Ear Clinic, University of Southern California, Los Angeles (Dr Brackmann).

Arch Otolaryngol Head Neck Surg. 1995;121(9):1052-1056. doi:10.1001/archotol.1995.01890090086017

Objective:  To describe the clinical and imaging features of metastatic melanoma to the cerebellopontine angle (CPA).

Design:  A case series study with world literature review.

Setting:  House Ear Clinic and St Vincent's Hospital, Los Angeles, Calif.

Patients:  Three cases of metastatic CPA tumors operated on at the House Ear Clinic.

Interventions:  All patients underwent surgical removal of CPA metastatic melanoma.

Main Outcome Measure:  Survival and duration of disease-free interval are reported.

Results:  Two patients died of melanoma within 5 months of diagnosis and resection of CPA melanoma metastases. One patient survived for 5 years after undergoing total resection of an isolated CPA melanoma metastasis. Magnetic resonance imaging features were not uniform.

Conclusions:  Metastatic melanoma to the CPA should be suspected in patients with a history of melanoma and a rapid progression of audiovestibular or facial nerve symptoms. Surgical removal of solitary metastases to the CPA may be valuable in patients without other melanoma focus; however, the longterm prognosis for patients with CPA melanoma is grim.(Arch Otolaryngol Head Neck Surg. 1995;121:1052-1056)

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