To determine the optimal treatment in pediatric patients with allergic fungal sinusitis (AFS).
A retrospective review of 10 patients diagnosed as having AFS.
Academic tertiary medical center.
Pediatric patients who fulfilled 5 criteria necessary for diagnosis of AFS: (1) type 1 hypersensitivity; (2) nasal polyposis; (3) characteristic computed tomographic scan; (4) histological evidence of eosinophilic mucus without evidence of fungal invasion into sinus tissue; and (5) a positive fungal stain or culture of sinus contents.
All patients were treated with functional endoscopic sinus surgery with removal of fungal debris. Adjuvant therapy included nasal irrigations, postoperative endoscopic cleanings, and systemic corticosteroids in 9 of 10 patients.
Mean Outcome Measure:
Clinical disease monitored endoscopically by means of an objective staging system.
Five patients were without disease (stage 0), 1 had allergic mucin and mucosal edema (stage I), 1 had allergic mucin and polypoid edema (stage II), and 3 had polyps and/or fungal debris (stage III).
The treatment and prognosis of pediatric AFS are similar to those of adult AFS. However, systemic corticosteroids should be weaned aggressively in children to minimize complications, particularly long-term growth retardation.Arch Otolaryngol Head Neck Surg. 1996;122:1381-1384
Kupferberg SB, Bent JP. Allergic Fungal Sinusitis in the Pediatric Population. Arch Otolaryngol Head Neck Surg. 1996;122(12):1381–1384. doi:10.1001/archotol.1996.01890240087019
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: