Computed tomography of the neck unsuspectingly revealed a large inhomogeneous soft tissue mass in the nasopharynx, with extension into the posterior nasal cavity (Figure 2). The mass diffusely deformed the nasopharynx and oropharynx and resulted in lateral bowing of the pterygoid plates on both sides. A subsequent cervical lymph node biopsy specimen demonstrated cytokeratin-positive tumor cells. The findings of other immunoperoxidase staining were consistent with NPC.