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Clinical Problem Solving: Pathology
February 2005

Pathology Quiz Case 2—Diagnosis

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Arch Otolaryngol Head Neck Surg. 2005;131(2):175-176. doi:10.1001/archotol.131.2.175

Postirradiation sarcoma is a rare long-term complication of radiation treatment. Taghian et al1 reported a 10-year cumulative incidence of 0.2% for sarcoma after radiation therapy. According to Laskin et al,2 osteosarcoma accounted for 13% of postirradiation sarcomas, and several authors have reported that 6% to 15% of patients with osteosarcoma of the head and neck had a history of irradiation.3

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