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Clinical Note
April 2005

Parotid Cysts in Children Infected With Human Immunodeficiency Virus: Report of 4 Cases

Author Affiliations

Author Affiliations: Departments of Infectious Diseases (Drs Morales-Aguirre, Patiño-Niño, and Gómez-Barreto), Epidemiology (Drs Mendoza-Azpiri, Villalobos-Acosta, and Cashat-Cruz), and Otolaryngology (Dr de la Torre), Hospital Infantil de México Federico Gómez, México DF, México.

Arch Otolaryngol Head Neck Surg. 2005;131(4):353-355. doi:10.1001/archotol.131.4.353

Cysts of the parotid glands were initially described in patients infected with human immunodeficiency virus (HIV) in 1988, as multiple cystic lesions associated with cervical lymphadenopathy and demonstrated by computed tomography and magnetic resonance imaging.1 Parotid enlargement has been reported in approximately 1% to 10% of the population infected with HIV-1, mainly in adults.2-5 In the pediatric HIV population, its prevalence is 1% to 10%.2 In a published series of Mexican children infected with HIV, a prevalence of 2.1% was demonstrated.3 However, information on parotid cysts in children with HIV/AIDS is scarce, as there is just 1 case report from 1991.5 Furthermore, in recent years a reduction in the incidence of this abnormality has been observed with the introduction of highly active antiretroviral therapy (HAART) with protease inhibitors. Therefore, no studies have evaluated the course of children infected with HIV who have parotid cysts. We present 4 cases observed in HIV-positive children treated at the Immunodeficiency Clinic of the Hospital Infantil de México Federico Gómez (Mexico City, México) from 1993 to 2003.4

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