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Clinical Note
February 21, 2011

Subglottic Stenosis Secondary to Lymphoplasmacytic Lymphoma

Author Affiliations

Author Affiliations: Division of Otolaryngology–Head and Neck Surgery, Dalhousie University, Halifax, Nova Scotia, Canada (Drs Brake, Hoyt, and Taylor); and Division of Otolaryngology–Head and Neck Surgery, Memorial University, St John’s, Newfoundland, Canada (Dr Lee).

Arch Otolaryngol Head Neck Surg. 2011;137(2):187-189. doi:10.1001/archoto.2010.253

Subglottic stenosis often presents a challenging problem for the otolaryngologist because its causes are many and varied, and its management is often difficult. The causes of adult-onset subglottic stenosis have been well documented and include trauma, collagen vascular diseases, benign and malignant neoplasms, and chronic inflammatory conditions.1 To our knowledge, we present the first successfully medically managed case of subglottic stenosis secondary to lymphoplasmacytic lymphoma (LPL), a malignant, infiltrative lymphoproliferative disorder of IgM producing monoclonal B lymphocytes. The clinical findings of LPL are commonly called Waldenstrom macroglobulinemia (WM).

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