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Clinical Problem Solving: Pathology
February 21, 2011

Pathology Quiz Case 2: Diagnosis

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Arch Otolaryngol Head Neck Surg. 2011;137(2):198-202. doi:10.1001/archoto.2010.248-b

Diagnosis: Low-grade fibromyxoid sarcoma (LGFMS)

Low-grade fibromyxoid sarcoma was first described by Evans1 in 1987. This initial report detailed 2 cases of metastatic sarcoma that had undergone previous surgery for deceptively bland-appearing soft-tissue neoplasms. In 1993, Evans2 added 10 additional cases of deep soft-tissue sarcomas to his original report, providing long-term follow-up that demonstrated a high rate of local recurrence and metastasis in 7 of 12 cases.

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