Vascular Evaluation in Laryngeal Diseases: Comparison Between Contact Endoscopy and Laser Doppler Flowmetry | Laryngology | JAMA Otolaryngology–Head & Neck Surgery | JAMA Network
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Original Article
December 2006

Vascular Evaluation in Laryngeal Diseases: Comparison Between Contact Endoscopy and Laser Doppler Flowmetry

Author Affiliations

Author Affiliations: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Arch Otolaryngol Head Neck Surg. 2006;132(12):1371-1374. doi:10.1001/archotol.132.12.1371
Abstract

Objective  To determine the efficacies of 2 methods for evaluating vascular changes in laryngeal diseases.

Design  Prospective comparative study.

Setting  University hospital.

Patients  Twenty-four adults planning to undergo laryngomicrosurgery for unilateral lesions in their vocal cords.

Intervention  Vascular evaluation was performed using contact endoscopy and laser Doppler flowmetry during laryngomicrosurgery.

Main Outcome Measures  Morphological and physiological variables of the vascular changes.

Results  Contact endoscopy examinations revealed changes in the fine vascular network patterns in the vocal cords. Hypervascularity was present in patients with polyps but not in those with nodules, and the degree of vascularity was variable in patients with malignant neoplasms. Patients with papillomas and patients in the postradiation therapy group showed hypovascularity with losses in the capillary network. Laser Doppler flowmetry revealed high mean blood flows in patients with polyps, dysplasia, and malignant neoplasms, whereas patients with papillomas and those in the postradiation therapy group had low blood flows. The variables measured by laser Doppler flowmetry and endoscopy were strongly correlated.

Conclusion  Evaluations of morphological and physiological changes of vascularity in laryngeal diseases are important for understanding their pathophysiology, and combining contact endoscopy and laser Doppler flowmetry is useful in such evaluations.

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