[Skip to Content]
[Skip to Content Landing]
April 1997

Baroreflex Dysfunction After Nasopharyngectomy and Bilateral Carotid Isolation

Author Affiliations

From the Department of Surgery and Division of Otolaryngology—Head and Neck Surgery, Stanford University Medical Center, Stanford, Calif. Dr Lee is now with the Columbia Presbyterian Medical Center, New York, NY. Dr Brown is now with the Department of Otolaryngology, King-Drew Medical Center, Los Angeles, Calif.

Arch Otolaryngol Head Neck Surg. 1997;123(4):434-437. doi:10.1001/archotol.1997.01900040080012

Baroreflex dysfunction (BRD) is an uncommon but perplexing clinical entity that occurs after an operation performed in the head and neck. Cases of BRD have occasionally been reported after bilateral carotid endarterectomies1-3 and in rare brain-stem tumors.4,5 We describe, for the first time to our knowledge, BRD in a patient after nasopharyngectomy and bilateral carotid isolation for recurrent nasopharyngeal carcinoma.

Ille O, Woimant F, Pruna A, et al.  Hypertensive encephalopathy after bilateral carotid endarterectomy .  Stroke . 1995;26:488-491.Crossref
Hirsch M, Kundi M, Hirschl MM, Liebisch B, Magometschnigg D.  Blood pressure responses after carotid surgery: relationship to postoperative baroreceptor sensitivity .  Am J Med . 1993; 94:463-468.Crossref
Robertson D, Beck C, Picklo M.  Classification of autonomic disorders .  Int Angiol . 1993;12:93-102.
Langford HG, Sanford R, Smith R, et al.  Neurogenic hypertension in man: Reis, Barman-Gebber or Carey syndrome .  J Hypertens . 1987; 5( (suppl 5) ):S467-S469.
Biaggioni I, Whetsell WO, Jobe J, Nadeau JH.  Baroreflex failure in a patient with central nervous system lesions involving the nucleus tractus solitarii .  Hypertension . 1994;23:491-495.Crossref
Fee WE, Roberson JB, Goffinet DR.  Long-term survival after surgical resection for recurrent nasopharyngeal cancer after radiotherapy failure .  Arch Otolaryngol Head Neck Surg . 1991;117: 1233-1236.Crossref
Robertson D, Hollister AS, Biaggioni I, et al.  The diagnosis and treatment of baroreflex failure .  N Engl J Med . 1993;329:1449-1455.Crossref
Aksamit TR, Floras JS, Victor RG, Aylward PE.  Paroxysmal hypertension due to sinoaortic baroreceptor denervation in humans .  Hypertension . 1987;9:309-314.Crossref
Berne RM, Levy MN.  Cardiovascular Physiology . 5th ed. St Louis, Mo: Mosby—Year Book Inc; 1986:167-171.
Maisel AS.  Beneficial effects of metoprolol in treatment of congestive heart failure .  Circulation . 1994; 90:1774-1780.Crossref
Tsunobuchi H, Katoh H, Takada M, et al.  The catecholamine concentrations of collected autologous blood during adrenalectomy for pheochromocytoma .  Jpn J Anesthesiology . 1995;44: 256-259.
Creager MA, Creager SJ.  Arterial baroreflex regulation of blood pressure in patients with congestive heart failure .  J Am Coll Cardiol . 1994; 23:401-405.Crossref