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December 2015, Vol 141, No. 12, Pages 1039-1148 | 2015 AHNS

In This Issue of JAMA Otolaryngology

Highlights

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. 2015;141(12):1039. doi:10.1001/jamaoto.2014.2187
Editorial

Time for a Change

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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1041. doi:10.1001/jamaoto.2015.2724

The Formula for Journal Success: Committed, Dedicated Reviewers—A Necessary Component

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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1042. doi:10.1001/jamaoto.2015.3074
Original Investigation

Oncologic Outcomes After Transoral Robotic Surgery : A Multi-institutional Study

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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1043-1051. doi:10.1001/jamaoto.2015.1508

This medical record review study supports the role of transoral robotic surgery in the treatment of patients with head and neck cancer, especially for those with oropharyngeal cancer.

Factors Associated With Hospital Length of Stay Following Fibular Free-Tissue Reconstruction of Head and Neck Defects: Assessment Using the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) Criteria

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1052-1058. doi:10.1001/jamaoto.2015.0756

Fibular free-tissue reconstruction of head and neck defects in patients with head and neck cancer was found to be associated with a longer-than-10-day hospital stay for procedures lasting longer than 11 hours and in patients who were ventilator dependent longer than 48 hours.

Selection of Ideal Candidates for Surgical Salvage of Head and Neck Squamous Cell Carcinoma: Effect of the Charlson–Age Comorbidity Index and Oncologic Characteristics on 1-Year Survival and Hospital Course

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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1059-1065. doi:10.1001/jamaoto.2015.2158

This study of patients with recurrent head and neck squamous cell carcinoma treated with salvage surgery recommends that medical comorbidity and age, primary T3/T4 stage, and disease-free interval be considered in selecting patients for surgical salvage.

The Cost of Hospice Services in Terminally Ill Patients With Head and Neck Cancer

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1066-1074. doi:10.1001/jamaoto.2015.2162

This retrospective cohort analysis uses data from the Surveillance, Epidemiology, and End Results–Medicare linked database to estimate monthly costs of all services used during the last months of life by patients with oral cavity and pharyngeal cancers.

Incidence of Suicide in Patients With Head and Neck Cancer

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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1075-1081. doi:10.1001/jamaoto.2015.2480

This cohort study of SEER data found that patients with head and neck cancer have more than 3 times the incidence of suicide compared with the general US population and that patients with hypopharyngeal and laryngeal cancer are at highest risk.

Effect of Gene Expression Classifier Molecular Testing on the Surgical Decision-Making Process for Patients With Thyroid Nodules

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1082-1088. doi:10.1001/jamaoto.2015.2708

This study examines surgical decisions made for patients with indeterminate thyroid nodules who underwent gene expression classifier (GEC) testing and compares actual vs recommended treatments to determine the effects on management of GEC testing.

Association of Thyroid Nodule Size and Bethesda Class With Rate of Malignant Disease

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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1089-1095. doi:10.1001/jamaoto.2015.1451

This medical record review demonstrates that large thyroid nodules (TNs) of any given Bethesda class are not associated with increased probability of malignant disease beyond that which is expected based on their cytological classification and suggest that smaller TNs pose a relatively increased risk of malignant disease.

Antibiotic Prophylaxis in Patients Undergoing Head and Neck Free Flap Reconstruction

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1096-1103. doi:10.1001/jamaoto.2015.0513

In a retrospective study to determine the ideal antibiotic prophylaxis in patients undergoing head and neck free flap reconstruction, Mitchell et al found ampicillin-sulbactam to be the preferred antibiotic for major clean-contaminated head and neck procedures.

Early Oral Tongue Squamous Cell Carcinoma: Sampling of Margins From Tumor Bed and Worse Local Control

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1104-1110. doi:10.1001/jamaoto.2015.1351

This review reports that margin sampling from the tumor bed is associated with worse local control in patients with oral tongue squamous cell carcinoma while margin assessment from resection specimens is associated with better local control.

Oncologic and Functional Outcomes of Surgical and Nonsurgical Treatment of Advanced Squamous Cell Carcinoma of the Supraglottic Larynx

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1111-1117. doi:10.1001/jamaoto.2015.0663

This retrospective review compares surgical vs nonsurgical treatment of advanced squamous cell carcinoma of the supraglottic larynx, finding that nonsurgical treatment as part of a larynx preservation protocol is associated with a higher likelihood of recurrence but has similar overall survival.

Treatment Outcomes for T4 Oropharyngeal Squamous Cell Carcinoma

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1118-1127. doi:10.1001/jamaoto.2015.0764

In evaluating oncologic outcomes for T4 oropharyngeal squamous cell carcinoma treated with primary surgical and nonsurgical therapies, the authors of this retrospective study found that primary surgical treatment may be associated with improved outcomes.

Aggressive Palliation and Survival in Anaplastic Thyroid Carcinoma

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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1128-1132. doi:10.1001/jamaoto.2015.2332

This comparative medical record review assesses the effect of aggressive treatment on survival and quality of life in patients with anaplastic thyroid carcinoma.

Mitigation of Tumor-Associated Fibroblast-Facilitated Head and Neck Cancer Progression With Anti–Hepatocyte Growth Factor Antibody Ficlatuzumab

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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1133-1139. doi:10.1001/jamaoto.2015.2381

This Original Investigation demonstrates that neutralizing tumor-associated fibroblast–derived hepatocyte growth factor with ficlatuzumab effectively mitigates c-Met signaling and decreases HNSCC proliferation, migration, and invasion.

Special Communication

Presidential Address

The Role of the Head and Neck Surgeon in the New World of Health Care Reform

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. 2015;141(12):1140-1144. doi:10.1001/jamaoto.2015.0651

The landscape of health care delivery in the United States is in the midst of irreversible and progressive changes that present tremendous opportunities to do maximal good for patients. Clinicians must embrace this opportunity to ensure this redesign is done properly and to the benefit of patients—not the bottom line of the health system.

Correction

Omitted Acknowledgment

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1095. doi:10.1001/jamaoto.2015.2080
Peer Reviewers List

JAMA Otolaryngology–Head & Neck Surgery Peer Reviewers in 2015

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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1146-1148. doi:10.1001/jamaoto.2015.3099
JAMA Otolaryngology–Head & Neck Surgery Masthead

JAMA Otolaryngology–Head & Neck Surgery

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. 2015;141(12):1040. doi:10.1001/jamaoto.2014.2188
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