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Year

Day

September 17, 2020
Viewpoint

SARS-CoV-2 Nasopharyngeal Swab Testing—False-Negative Results From a Pervasive Anatomical Misconception

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 17, 2020. doi:10.1001/jamaoto.2020.2946

This Viewpoint describes how a commonly held false presumption of nasal and nasopharyngeal anatomy may contribute to false-negative results in severe acute respiratory syndrome coronavirus 2 testing.

Original Investigation

Efficacy of Timolol in a Novel Intranasal Thermosensitive Gel for Hereditary Hemorrhagic Telangiectasia–Associated Epistaxis: A Randomized Clinical Trial

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 17, 2020. doi:10.1001/jamaoto.2020.3025

This randomized clinical trial uses data from existing patients at a tertiary care facility to assess the efficacy of intranasal thermosensitive timolol gel in treating moderate-to-severe recurrent hereditary hemorrhagic telangiectasia–associated epistaxis.

In Vitro Efficacy of a Povidone-Iodine Nasal Antiseptic for Rapid Inactivation of SARS-CoV-2

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 17, 2020. doi:10.1001/jamaoto.2020.3053

This cross-sectional study assesses the efficacy of nasal povidone-iodine against in vitro transmission of severe acute respiratory syndrome coronavirus 2.

Clinical Challenge

Pathology

A Radiolucency Associated With an Impacted Mandibular Canine Tooth in an Adult Man

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 17, 2020. doi:10.1001/jamaoto.2020.2589

A man in his 40s presented with mobility of the anterior mandibular dentition; clinical examination revealed fullness on the mentolabial fold, but no gross facial asymmetry or mental nerve paresthesia. What is your diagnosis?

Radiology

An Unusual Retropharyngeal Lesion

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 17, 2020. doi:10.1001/jamaoto.2020.2703

A female smoker in her 50s was referred for hyperparathyroidism and a multinodular goiter. What is your diagnosis?

Observation

Noncongenital Pediatric Mature Teratoma of the Mandible

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 17, 2020. doi:10.1001/jamaoto.2020.2572

This case report describes a young African American girl who presented with a 2-month history of left cheek swelling and pain associated with an enlarging jaw mass that was determined to be a mature teratoma.

From the American Head and Neck Society

Hyperprogression of a Sinonasal Squamous Cell Carcinoma Following Programmed Cell Death Protein-1 Checkpoint Blockade

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 17, 2020. doi:10.1001/jamaoto.2020.2584

This case report describes man in his 60s who presented with a maxillary sinus squamous cell carcinoma and experienced hyperprogression following treatment with pembrolizumab.

September 10, 2020
Viewpoint

COVID-19, Disparities, and Opportunities for Equity in Otolaryngology—Unequal America

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 10, 2020. doi:10.1001/jamaoto.2020.2874

This Viewpoint discusses the disproportionate burdens related to COVID-19 experienced by minority populations as well as strategies to limit disparities in health care, access, and outcomes.

Original Investigation

Association of Hypertension With the Risk and Severity of Epistaxis

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 10, 2020. doi:10.1001/jamaoto.2020.2906

This cohort study uses a nationwide population cohort to evaluate the risk of epistaxis in patients with hypertension and assesses the association of hypertension with the methods of managing epistaxis.

Observation

Spontaneous Cerebrospinal Fluid Leak in a Transgender Man: Is Testosterone Therapy a Risk Factor?

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 10, 2020. doi:10.1001/jamaoto.2020.2394

This case report describes a transgender man in his 20s who presented with 9 months of right-sided rhinorrhea and spontaneous drainage of clear, salty nasal discharge consistent with idiopathic intracranial hypertension.

Sinonasal Teratocarcinosarcoma—A Rare and Highly Aggressive Neoplasm

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 10, 2020. doi:10.1001/jamaoto.2020.2413

This case report describes a man in his 20s who presented with a 2-month history of epistaxis and progressive nasal obstruction and was subsequently diagnosed with a sinonasal teratocarcinosarcoma.

Comment & Response

Incomplete Picture of Otolaryngologist Performance in the Merit-Based Incentive Payment System

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 10, 2020. doi:10.1001/jamaoto.2020.2599

Incomplete Picture of Otolaryngologist Performance in the Merit-Based Incentive Payment System—Reply

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 10, 2020. doi:10.1001/jamaoto.2020.2602
September 3, 2020
Viewpoint

Timing of Tracheostomy for Patients With COVID-19 in the ICU—Setting Precedent in Unprecedented Times

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2630

This Viewpoint examines the timing of performing tracheostomies, which are aerosol-generating procedures that may cause increased risk of COVID-19 transmission to health care workers.

Reflections

Hearing From the COVID-19 Epicenter—A Neurotologist’s Reflection From the Front Lines

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2532

This essay highlights the lessons to be learned from the COVID-19 pandemic on the importance of recognizing communication difficulties among those with hearing impairment.

Original Investigation

From the American Head and Neck Society

Outcomes of a Telephone-Based Questionnaire for Follow-up of Patients Who Have Completed Curative-Intent Treatment for Oral Cancers

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2404

This diagnostic study uses data from patients treated for oral cancer at a tertiary care cancer center in India to investigate the clinical value of a telephone-based questionnaire in detecting cancer recurrence during follow-up evaluation.

Predictors of Behavioral Changes After Adenotonsillectomy in Pediatric Obstructive Sleep Apnea: A Secondary Analysis of a Randomized Clinical Trial

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2432

This secondary analysis compares the use of objective physiological measures with subjective caregiver symptom reports to identify the association between sleep disruption with or without intermittent hypoxemia and behavior in children who underwent surgical treatment for obstructive sleep apnea.

Association of Poorer Hearing With Longitudinal Change in Cerebral White Matter Microstructure

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2497

This cohort study examines the association of poorer hearing with baseline and change in white matter microstructure among older adults.

Invited Commentary

Mapping the Brain Effects of Hearing Loss: The Matter of White Matter

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2528
Clinical Challenge

Endoscopy

Progressive Upper Airway Obstruction and Dysphagia in a Child With Supraglottic Edema

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2577

A 9-year-old boy presents with progressive dyspnea, snoring, dysphagia, and weight loss; biopsy and culture results revealed diffuse non-necrotizing granulomas and oropharyngeal flora with negative acid-fast bacilli and Grocott methenamine silver stains. What is your diagnosis?

Observation

Reconstruction of Nasopharynx Defect Using a Free Flap After Endoscopic Nasopharyngectomy—Feasibility and Technical Considerations

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2187

This case report describes of a man in his 60s with nasopharyngeal carcinoma who underwent concurrent chemoradiotherapy and subsequently developed local recurence.

Atypical Presentation of Langerhans Cell Histiocytosis of the Skull

Abstract Full Text
JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2399

This case report describes a man in his 20s who presented with a 4-week history of progressive swelling of the midline forehead, recurrent headache, and sinus pain, and was subsequently diagnosed with Langerhans cell histiocytosis.

Comment & Response

Tracheostomy During COVID-19 Pandemic—In Search of Lost Timing

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2627

Tracheostomy During COVID-19 Pandemic—In Search of Lost Timing—Reply

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2633
Correction

Omission of Funding Source

Abstract Full Text
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JAMA Otolaryngol Head Neck Surg. Published online September 3, 2020. doi:10.1001/jamaoto.2020.2950
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