Best estimates place the number of individuals 13 to 24 years of age who are newly diagnosed with human immunodeficiency virus (HIV) infection each year at more than 10 000.1 This represents approximately 20% of all newly diagnosed cases of HIV annually. While this number is large, the most troubling statistic concerning HIV infection among youth is that more than 48% of those youth who are infected are unaware of their status as opposed to 25% of infected individuals in all other age groups.2