The principal difficulty attending intravenous injections and transfusion in young infants has always been a technical one due to the extremely small size of the veins. The suggestion of Helmholtz, that in hemorrhagic disease of the newborn transfusion could be more easily performed by using the longitudinal sinus, appeared to be of the greatest importance in this connection. The longitudinal sinus in the infant is a large vein easily accessible through the open fontanel. If the employment of this route in performing transfusion avoids the principal technical difficulty, it is available not only for transfusion in hemorrhagic disease of the newborn, but also for the giving of intravenous injections and medication. That certain forms of medication, as well as the giving of fluid for the purpose of stimulation or of supplying loss to the blood, are best given directly into the blood itself rather than by mouth or by the
DUNN CH. INTRAVENOUS GLUCOSE INJECTIONS IN INFANCY. Am J Dis Child. 1917;14(1):52–56. doi:10.1001/archpedi.1917.01910070059007
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