At present there is considerable difference of opinion as to the value of vaccines in the treatment of disease. It may be said, perhaps, that there is a tendency to grant them a less important position in therapeutics than was the case a few years ago. The use of vaccines in whooping cough, however, is still highly recommended by many who have had occasion to use this therapy in private and institutional practice. Recently Luttinger1 reported favorably on the use of this vaccine after an experience with a whooping cough clinic in New York City. However, Van Sholle, Blum and Smith2 concluded from the same clinical material that "more observations and more critical observations with controls for comparison must be made before the case can be made out for the curative and prophylactic value of pertussis vaccine." Their results were quite the opposite to those of Luttinger. Shaw
BARENBERG LH. THE CURATIVE AND PROPHYLACTIC VALUE OF VACCINES IN PERTUSSIS. Am J Dis Child. 1918;16(1):23–29. doi:10.1001/archpedi.1918.01910130030003
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