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August 1919

POSTINFLUENZAL ENCEPHALITIS

Am J Dis Child. 1919;18(2):83-87. doi:10.1001/archpedi.1919.04110320012002
Abstract

INTRODUCTION  The pandemic of influenza which in the fall of last year spread with such alarming virulence over two continents spared no age. Though perhaps less frightful in its ravages among infants and children, there were many serious complications. Among these was a group of very unusual symptoms related to the central nervous system. Sudden onset, two or three weeks after an attack of influenza, of stupor or coma, paralysis with frequent cranial nerve involvement and a normal cerebrospinal fluid were the most significant manifestations. A study of eight such cases from the Pediatric Service of Mount Sinai Hospital form the basis of this paper.

HISTORY  To modern observers, it seemed for a while to be a new symptom complex, but as early as 1712, during an epidemic of influenza, Zuelzer1 made note of peculiar drowsy states complicating many cases. In the course of the extensive epidemic of 1890

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