Intraperitoneal injection is one of the accepted methods of parenteral administration of fluid. In conditions such as diarrhea, in which dehydration is extreme, repeated administration of fluid is often necessary—under the skin, into the veins and into the peritoneal cavity. The question of the absorption of fluid by the peritoneum is, therefore, a matter of very practical import.
Postmortem examination of infants that received fluid intraperitoneally a short time before death, has already thrown some light on the problem of absorption. Blackfan and Maxcy1 conclude that absorption is rapid. They record the recovery of 20 c.c. of fluid in an infant weighing 20 pounds, that received 250 c.c. eighteen hours, and 200 c.c. six hours before death. The fluid was clear yellow; the peritoneum was glistening and no mention was made of deposition of fibrin, cellular exudate or other evidence of inflammatory reaction.
Our own necropsy findings indicate varying
DENZER BS, ANDERSON AF. THE ABSORPTION OF FLUID INJECTED INTO THE PERITONEAL CAVITY. Am J Dis Child. 1921;21(6):565–574. doi:10.1001/archpedi.1921.01910360048006
Customize your JAMA Network experience by selecting one or more topics from the list below.