The Medical Research Committee of Great Britain, in its report on rickets, published in 1918, came to the conclusion that "in spite of a most varied and extensive research we have practically no real knowledge of the nature or causation of this widespread malady, or of the factors which determine its onset."1 There are two widely divergent theories as to its etiology—the hygienic and the dietetic, the pendulum swinging sometimes in the one and sometimes in the other direction. As will be remembered, Kassowitz, one of the best known students of this disorder, maintained the opinion that rickets came about from breathing noxious gases, which accumulated in cadly ventilated rooms.2 Von Hansemann ascribed its development to "domestication," including under this broad term all the harmful influences which result from modern civilization.3 Findlay and Paton, in the report just referred to, emphasize the etiologic importance of inadequate air
HESS AF, UNGER LJ. AN INTERPRETATION OF THE SEASONAL VARIATION OF RICKETS. Am J Dis Child. 1921;22(2):186–192. doi:10.1001/archpedi.1921.04120020083006
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