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October 1922


Author Affiliations

From the Pediatric Department of New York Nursery and Child's Hospital and the Department of Pediatrics, Cornell Medical College.

Am J Dis Child. 1922;24(4):346-355. doi:10.1001/archpedi.1922.04120100079009

Walker has notably added to our better understanding of asthma by giving an extensive working foundation. Many other workers have since contributed large series of studied cases. They all, however, report a certain number of cases in which the causative agents could not be found. Walker,1 for example, found 50 per cent, which did not react to any proteins. In the most recent classification by Rackemann,2 41 per cent. of the true asthmatics did not react to proteins. Naturally, in work of this kind there are many factors which make it difficult to study cases completely, and were it possible for investigators to do so more exhaustively, the unclassified group would undoubtedly be smaller. Our series of cases offers an example of just such a group which would have remained unclassified had it not been our good fortune to discover the offending protein in the first case which