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January 1923


Author Affiliations

From the Children's Clinic of Minneapolis.

Am J Dis Child. 1923;25(1):46-54. doi:10.1001/archpedi.1923.01920010051002

Samuel Gee described celiac disease in 1888. In 1921, Reginald Miller,1 in compiling a retrospect of the literature concerning it, mentioned about fifty papers, but even his excellent bibliography is not complete. A study of this literature makes it evident that, in general, the accounts of celiac disease, celiac infantilism, Herter's infantilism, intestinal infantilism, acholia, pancreatic infantilism, pancreatic insufficiency and of a certain type of chronic intestinal indigestion agree fairly well in the description of a condition which we can hypothetically consider to be one specific morbid entity.

The disease has never been recognized in a breast fed infant. In its typical form it is always chronic. The children suffering with it are undersize and underweight. The roentgen ray shows delayed skeletal development and the muscles are small, soft and weak. This weakness is most noticeable in the legs. The abdomen is distended. The stools are voluminous, gray, greenish