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February 1923


Author Affiliations

Fellow in Pediatrics, University of Minnesota MINNEAPOLIS; ST. PAUL
From the Department of Pharmacology, University of Minnesota.

Am J Dis Child. 1923;25(2):107-129. doi:10.1001/archpedi.1923.01920020024004

Blood transfusion in infants and children is a recognized therapeutic procedure. In the past, the site of transfusion has been limited to the superior longitudinal sinus in the region of the anterior fontanel, or to the direct exposure of some vein, preferably in the elbow.

The anterior fontanel route, popularized by Helmholz1 in 1915, affords an excellent method in infants in whom this structure is accessible. This approach, however, has its limitations. Fischer,2 Lowenburg,3 Unger,4 and others, have pointed out the dangers inherent in puncturing the superior longitudinal sinus.

In older infants, those more than 18 months of age, the fontanel is not usually patent, and the only other procedure remaining is the exposure of a vein and the injection of the donor's blood. We need not go into a discussion concerning the technical considerations involved in this method. It is conceded that the number of