It has been supposed for some time that the T-wave in the electrocardiogram is high in hyperthyroidism and low, absent or even inverted in hypothyroidism. White and Aub1 made a study of a series of twenty-seven cases of thyroid disease in adult patients in this hospital, to determine if there was any parallelism between the basal metabolism and the amplitude of the electrocardiographic T-wave. They found a very limited parallelism, practically none in hyperthyroid cases, but a considerable degree in hypothyroid cases. It was observed that the administration of thyroid in cases of hypothyroidism caused the T-wave to increase under treatment. Zondek2 reported observations on the heart in myxedema, in 1918 and 1919, in which he found that the heart, shown by roentgenogram, was enlarged, that the pulse action was weak with a slow rate, and that the blood pressure was normal. In the electrocardiogram he found both
THACHER C. THE ELECTROCARDIOGRAM IN CRETINISM AND IN MONGOLIAN IDIOCY. Am J Dis Child. 1924;28(1):25–27. doi:10.1001/archpedi.1924.04120190028003
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