Jaundice occurs in the new-born baby so frequently that its appearance is considered a mere physiologic event, and owing to its usually mild and transient course it has caused no serious concern to the pediatrician. It is obvious that, owing to its frequency in the postnatal period, jaundice will usually be an accompanying symptom of pathologic conditions in the new-born baby. In these cases our diagnostic and therapeutic efforts will concentrate on the chief disease, and the jaundice does not warrant any other consideration than the mere physiologic icterus of the new-born. Cases, however, in which the jaundice is the outstanding symptom of a severe illness deserve serious consideration. The underlying pathologic changes in one group of cases of this general type will be clearly indicated by the acholic feces as an obstruction of the outflow of the bile, due to malformation of the large bile ducts. In another group, the
KLEMPERER P. ICTERUS GRAVIS OF THE NEW-BORN. Am J Dis Child. 1924;28(2):212–226. doi:https://doi.org/10.1001/archpedi.1924.04120200082009
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